The beautiful intergalactic bounty hunter Iria has returned to Earth. She is assigned a new android trainee. Unfortunately, inside the android resides the most cunning combat life form in the universe - a vicious Zeiram unit! When the android is damaged during combat, Zeiram emerges and begins to terrorize Iria and her comrades with its wide variety of weapons. Trapped in a dimensional Zone, Iria will have to face down the monster one-on-one if anyone is going to get out alive.