With 3 of her husbands dying a tragic death, Ina (Ai-Ai de las Alas) has dealt with some unlucky events in her life and struggles to raise her 12 children. They grow up resenting her which causes a rift in their family dynamic. However, she is poised to be better and tries to find ways to build a relationship with each of her children. "Ang Tanging Ina" is a Filipino comedy film from Star Cinema.