Young Dr. Kildare presses his mentor, Dr. Gillespie, to go on a much-needed vacation while he takes a case caring for the daughter of a Wall Street tycoon. Kildare pretends to be a friend of the family to examine Nancy and learns she has blinding headaches. After the housekeeper confides that Nancy she has a tumor like the one that killed her mother, Kildare struggles to make a proper diagnosis.